Commonly prescribed antidepressants include duloxetine (Cymbalta), fluoxetine (Prozac), paroxetine (Paxil), sertraline (Zoloft) and venlafaxine (Effexor). How they can cause fatigue: Fatigue is a common side effect of antidepressant medications, especially during early weeks of treatment. Trazodone can make you sleepy by blocking these histamines. This is similar to the effects of another common antihistamine, Benadryl (diphenhydramine). In a research study, trazodone also seemed to improve slow-wave or deep sleep. First, upon feeling the symptoms of a cold coming on, take an emergen-c packet. And one each day that you feel sick. Second, make an effort to drink a lot of fluids, whether it's orange juice, water, tea, or what have you its good to stay hydrated. Thirdly, eat things that will not upset your stomach. Constant feelings of exhaustion may also be a sign of anemia in some cases. Even if you get a full eight hours of sleep, having an iron deficiency can lead to feeling low in energy, if left Flexeril is likely to make you sleepy or impair your judgment time. This may be beneficial in aiding sleep; however, you should avoid operating machinery, driving, or performing tasks that require mental alertness while taking this medicine. Avoid alcohol while taking this medicine. Alcohol may potentiate the side effects of Flexeril. Resolve to move a little more, drink a little less, eat a little healthier, sleep a little better and destress a lot. To fall asleep fast, experts recommend keeping a regular schedule, reducing Clinical trial data show that people using Lexapro were more likely to report insomnia. In one trial, 9% reported insomnia on Lexapro, compared to 4% on placebo.People in the placebo group do not Melatonin can cause symptoms like nausea, vomiting, or stomach cramps. Taking too much melatonin can lead to stomach irritation. Some people may also be more sensitive to oral melatonin regardless of how much they take. If your stomach discomfort worsens while taking melatonin, contact your healthcare provider. 6. 6Fxx.