Best Vitamin C Serums for Sensitive Skin. 1. Dr. Barbara Sturm The Good C Vitamin C Serum, $145. Pros: Lightweight, super nourishing, easy to blend, balances the skin, spa-like quality. Cons: None Best Overall: Eau Thermale Avène RetrinAL 0.1 Intensive Cream, $79. Best for Mature Skin: La Roche-Posay Redermic R Retinol Cream, $55. Best for Sensitive Skin: Obagi Medical Retivance Skin ISDIN Melatonik 3-in-1 Night Serum. For an overnight option, both Dr. Garshick and Dr. Castilla recommend Isdin's 3-in-1 serum that uses bakuchiol, as well as melatonin and vitamin C, to protect Best for Beginners: The Inkey List Retinol Anti-Aging Serum, $13. Best for Wrinkles: Neutrogena Rapid Wrinkle Repair Regenerating Cream, $25. Best for Mature Skin: Kate Somerville +Retinol Vitamin The CeraVe Resurfacing Retinol includes 0.3 percent retinol and three types of ceramides to work deeply on skin while smoothing it. The formulation also includes licorice root extract, which helps CeraVe Resurfacing Retinol Serum. $16 at Amazon. Available both over the counter and by prescription, topical retinoids are a form of Vitamin A compounds, Dr. Zeicher says. While topical retinoids To further support the efficacy of their retinol serum, First Aid Beauty conducted a consumer perception study that found impressive results. After just four weeks of use, 90% of participants reported smoother, more radiant skin, while 83% saw a reduction in the appearance of wrinkles and fine lines. L’Oréal Paris Revitalift Derm Intensives Hyaluronic Acid + Caffeine Hydrating Eye Serum. $20 at Amazon. Ahead, find the best eye creams for puffiness that address additional concerns like uP19JZ.